Pulmonary sarcoidosis with arterial involvement

Abstract

Case Presentation: We present the case of a 43-year-old woman with a two-year history of progressive dyspnea, dry cough, and a family history of sarcoidosis. Imaging revealed multiple pulmonary nodules, the largest measuring $2.7\times1.4$ cm.

Diagnosis: Histopathological analysis of a lung biopsy confirmed necrotizing sarcoid granulomatosis (NSG) after ruling out fungal and mycobacterial infections.

Outcome: Following the administration of prednisone, the patient developed massive pulmonary thromboembolism with hemodynamic instability and died.

Conclusion: NSG is an under-recognized condition that can mimic pulmonary neoplasia or other granulomatous diseases. Despite generally having a benign course, this case highlights an unusual and fatal outcome involving recurrent thromboembolisms.

Keywords: Granuloma; Granulomatosis with Polyangiitis; Sarcoidosis.

Clique aqui

• Data de Publicação: 16/05/2021
• Autores: Adriane Souza da Paz1 , João Carlos Coelho2 , Bartira Melo3 , Ana Luísa Pedreira1 , Mittermayer Barreto Santiago1,2,3 