Evaluation of CoronaVac and CoviShield Vaccines on SARS-CoV-2 Infection in Healthcare Workers in Salvador, Brazil

Background: There are scarce data on the prevalence and disease presentation of HIV in patients with tuberculosis (TB) and dysglycemia (diabetes [DM] and prediabetes [PDM]), especially in TB-endemic countries.

Methods: We assessed the baseline epidemiological and clinical characteristics of patients with culture-confirmed pulmonary TB, enrolled in a multicenter prospective cohort in Brazil (RePORT-Brazil) during 2015–2019. Dysglycemia was defined by elevated glycated hemoglobin and stratified as PDM or DM. Additionally, we used data from TB cases obtained through the Brazilian National Notifiable Diseases Information System (SINAN), during 2015–2019. In SINAN, diagnosis of diabetes was based on self-report. Logistic regression models were performed to test independent associations between HIV, dysglycemia status, and other baseline characteristics in both cohorts.

Keywords: viral load; SARS-CoV-2; vaccines

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• Data de Publicação: 27/10/2023
• Autores: Jesús Enrique Patiño Escarcina,Felipe de Jesus Souza Felipe de Jesus Souza ,Ana Keila Carvalho Vieira Da Silva ,Keile Kemyly Assis Da Silva ,Ruan Barbosa Souza ,Saulo Reis Nery Santos and Eduardo M. Netto